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Research Letter
February 7, 2020

Epidemiologic and Clinical Characteristics of Novel Coronavirus Infections Involving 13 Patients Outside Wuhan, China

Author Affiliations
  • 1College of Respiratory and Critical Care Medicine, Chinese PLA General Hospital, Beijing, China
  • 2Beijing Tsinghua Changgung Hospital, Tsinghua University School of Medicine, Beijing, China
  • 3Institute for Precision Medicine, Tsinghua University, Beijing, China
  • 4Department of Infectious Diseases, Beijing Anzhen Hospital, Beijing, China
  • 5Section of Pulmonary and Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, Connecticut
JAMA. Published online February 7, 2020. doi:10.1001/jama.2020.1623

In December 2019, cases of pneumonia appeared in Wuhan, China. The etiology of these infections was a novel coronavirus (2019-nCoV),1,2 possibly connected to zoonotic or environmental exposure from the seafood market in Wuhan. Human-to-human transmission has accounted for most of the infections, including among health care workers.3,4 The virus has spread to different parts of China and at least 26 other countries.1 A high number of men have been infected, and the reported mortality rate has been approximately 2%, which is lower than that reported from other coronavirus epidemics including severe acute respiratory syndrome (SARS; mortality rate, >40% in patients aged >60 years)5 and Middle East respiratory syndrome (MERS; mortality rate, 30%).6 However, little is known about the clinical manifestations of 2019-nCoV in healthy populations or cases outside Wuhan. We report early clinical features of 13 patients with confirmed 2019-nCoV infection admitted to hospitals in Beijing.