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Clinical Trials Update
February 25, 2020

Platelet-Rich Plasma Doesn’t Facilitate Achilles Tendon Healing

JAMA. 2020;323(8):701. doi:10.1001/jama.2020.1006

Platelet-rich plasma provided no benefit after acute Achilles tendon rupture, a trial in the BMJ reported. The autologous whole-blood product, which delivers a high concentration of platelets, leucocytes, growth factors, and cytokines, is used extensively in sports and orthopedic medicine.

Participants included 230 adults at 19 UK hospitals with acute Achilles tendon rupture that had occurred in the previous 12 days and was being managed without surgery. Patients were randomized to receive an injection of platelet-rich plasma or placebo (dry-needle injection); all participants also received standard rehabilitation care.

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