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October 13, 1945


JAMA. 1945;129(7):495-500. doi:10.1001/jama.1945.02860410011003

In the period from Jan. 1, 1928 to July 1, 1944, 225 casesof tularemia were observed in the Charity Hospital of Louisiana at New Orleans. As this is a large series of cases to be studied in a single institution, analysis of these cases from the clinical point of view seems worth while. We shall not attempt an exhaustive survey of the literature, as it is believed that the size of this group of cases will provide a representative sampling of the difficulties in diagnosis and treatment of tularemic infections in general.

It is doubtful whether tularemia is a growing disease in incidence as well as in morbidity and mortality. The apparent increase in some sections of the country is probably based on a more general awareness and increasing recognition of the disease. The diagnosis of tularemia is to be considered in any acute febrile illness, and the remarkable similarity