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October 20, 1945

TRANSVERSE MYELOPATHY FOLLOWING RECOVERY FROM PNEUMOCOCCIC MENINGITIS: TREATED WITH PENICILLIN INTRATHECALLY REPORT OF CASE, WITH A NOTE ON CURRENT METHODS OF THERAPY

JAMA. 1945;129(8):547-550. doi:10.1001/jama.1945.02860420015006
Abstract

Widespread use of penicillin has aroused interest in the management of acute bacterial meningitis. Perhaps the most fatal type has been pneumococcic meningitis, but recent reports have offered hope that at long last we possess a potent weapon against this disease. The case herein reported illustrates the occurrence of an unusual complication, transverse myelopathy, in the course of recovery from acute bacterial meningitis. This sequel is of particular current interest because of the recent report by Sweet and his co-workers1 of severe though reversible spinal cord or nerve root damage following recovery from pneumococcic meningitis treated with penicillin intrathecally.

REPORT OF CASE  A woman aged 66, admitted to the hospital in a state of restless stupor, had awakened that morning at 8, according to her physician, complaining of pain in and behind her left ear. When he saw her one hour later he had to irrigate the external canal

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