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October 20, 1945

BILATERAL OPTIC ATROPHY AS A SEQUELA TO THROMBOCYTOPENIC PURPURA

JAMA. 1945;129(8):550-551. doi:10.1001/jama.1945.92860420001007
Abstract

Bilateral optic atrophy is rarely observed as a sequela in patients suffering from thrombocytopenic purpura.

A recent review of the literature by Watkins, Wagener and Brown1 tends to show the rather infrequent observance of "choked disk" in purpura hemorrhagica, but optic nerve atrophy was not noted in these cases.

Michail2 reported 1 case of bilateral optic atrophy as following purpura hemorrhagica, in which irradiation of the spleen caused a disappearance of the petechiae but the eye condition did not improve. He also cites a case reported by Narog and another by Schall in which hemorrhages into the retina were present.

Several cases of intracranial hemorrhage following purpura hemorrhagica have been reported at necropsy and reviewed by Alpers and Duane.3 These cases involve cerebral, ventricular and meningeal

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