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Clinical Trials Update
March 24/31, 2020

Online Mindfulness Therapy Improves Residual Depression

JAMA. 2020;323(12):1124. doi:10.1001/jama.2020.2446

Patients whose depression lingered after treatment had less severe residual symptoms, higher rates of remission, and lower rates of relapse following online mindfulness-based cognitive therapy, a trial in JAMA Psychiatry reported.

The study’s 460 participants, who had achieved partial remission with antidepressants, psychotherapy, or both, were randomized to usual depression care (UDC) or to Mindfulness Mood Balance (MMB) plus UDC. Over 3 months, the 8-session online intervention taught skills to prevent dysfunctional thinking patterns, with minimal phone or email support.