Antibodies in Infants Born to Mothers With COVID-19 Pneumonia | Infectious Diseases | JAMA | JAMA Network
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Research Letter
March 26, 2020

Antibodies in Infants Born to Mothers With COVID-19 Pneumonia

Author Affiliations
  • 1Department of Laboratory Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China
  • 2Department of Gynaecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, China
JAMA. 2020;323(18):1848-1849. doi:10.1001/jama.2020.4861

Tests for IgG and IgM antibodies for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) became available in February 2020. On March 4, 2020, the seventh edition of the New Coronavirus Pneumonia Prevention and Control Protocol for the novel coronavirus disease 2019 (COVID-19) was released by the National Health Commission of the People’s Republic of China and added serological diagnostic criteria.1 A previous study of 9 pregnant women and their infants found no maternal-infant transmission of SARS-CoV-2 based on reverse transcriptase–polymerase chain reaction (RT-PCR).2 We applied these new criteria to 6 pregnant women with confirmed COVID-19 and their infants because serologic criteria would allow more detailed investigation of infection in newborns.

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