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April 9, 2020

Updated CDC Recommendations for Universal Hepatitis C Virus Screening Among Adults and Pregnant Women: Implications for Clinical Practice

Author Affiliations
  • 1Department of Pediatrics, Medical College of Wisconsin, Milwaukee
  • 2Children’s Hospital of Wisconsin, Milwaukee
  • 3Department of Gynecology and Obstetrics, Johns Hopkins Medical Institutions, Baltimore, Maryland
JAMA. 2020;323(22):2258-2259. doi:10.1001/jama.2020.3693

Acute hepatitis C virus (HCV) infections in the US have increased more than 3-fold since 2010.1 In 2017, there were an estimated 44 700 cases of acute HCV infection in the US,2 which is more than the 37 377 cases of HIV reported.3 In addition, there are now more deaths annually from HCV infection than from HIV in the US2,3; in 2017, HCV infection accounted for 17 253 deaths2 and HIV accounted for 15 971 deaths.3 Deaths related to HCV infection are considered to be largely preventable because therapies are now readily available that can achieve virological cure (defined as undetectable HCV infection in the blood for ≥12 weeks after completing treatment, and referred to as a sustained virological response).

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