In 1934 we1 reported experimental and clinical observations on the use of divinyl ether as a general anesthetic. At that time our experience was based on the use of divinyl ether in 461 patients. We were led to conclude that "from the standpoint of induction, maintenance and recovery the anesthetic is satisfactory.... Its exact position in relation to the other general anesthetics now being used will have to await a more extensive clinical experience."
The use of the anesthetic has been extended to a number of the clinical departments of the hospital, and in certain of them it has become the anesthetic of choice when general anesthesia is required. The data in this paper have been obtained from 2,675 anesthetizations. This is by far the largest series reported. We believe that it is now possible more clearly to define the usefulness of this substance as an anesthetic agent.
RAVDIN IS, ELIASON EL, COATES GM, et al. DIVINYL ETHER: A REPORT OF ITS FURTHER USE AS A GENERAL ANESTHETIC. JAMA. 1937;108(14):1163–1167. doi:10.1001/jama.1937.02780140019006
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