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Comment & Response
April 28, 2020

Premature Menopause and Risk for Cardiovascular Disease

Author Affiliations
  • 1INSERM U1018, Villejuif, France
JAMA. 2020;323(16):1616. doi:10.1001/jama.2020.2533

To the Editor Venous thromboembolism (VTE) is a global health concern because of its significant morbidity and mortality. To our knowledge, few studies have investigated the associations of reproductive life characteristics with VTE risk in women.1 Analysis of UK Biobank data by Dr Honigberg and colleagues2 highlights the role of premature natural or surgical menopause in increasing both atherosclerotic and nonatherosclerotic cardiovascular risk, including VTE risk.

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