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Research Letter
May 12, 2020

Rural-Urban Differences in Cardiovascular Mortality in the US, 1999-2017

Author Affiliations
  • 1Sanford School of Public Policy, Duke University, Durham, North Carolina
  • 2Brigham and Women’s Hospital Heart and Vascular Center, Harvard Medical School, Boston, Massachusetts
  • 3Division of Cardiovascular Prevention and Wellness, Houston Methodist DeBakey Heart and Vascular Center, Houston, Texas
  • 4Department of Medicine, Veterans Affairs Boston Healthcare System, Boston, Massachusetts
  • 5Verily Life Sciences, South San Francisco, California
JAMA. 2020;323(18):1852-1854. doi:10.1001/jama.2020.2047

Wide variation in cardiovascular disease age-adjusted mortality rates (AAMRs) has been noted among counties in the US.1 Rural residents experience higher death rates compared with residents of urban areas, particularly from potentially preventable causes.2 We examined temporal trends in cardiovascular disease AAMRs overall and across subgroups stratified by rural-urban area designation in the US.