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Research Letter
May 5, 2020

Case Series of Transcutaneous Magnetic Stimulation for Ventricular Tachycardia Storm

Author Affiliations
  • 1Division of Cardiology, Hospital of the University of Pennsylvania, Philadelphia
  • 2Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia
JAMA. Published online May 5, 2020. doi:10.1001/jama.2020.3833

Numerous studies suggest the therapeutic benefit of autonomic neuromodulation to reduce cardiac sympathetic input in patients with ventricular tachycardia storm.1 Neuromodulation includes local blockade of the left stellate ganglion, a significant source of cardiac sympathetic innervation.2 Transcutaneous magnetic stimulation (TCMS) has a role in noninvasive and nondestructive modulation of nervous system activity.3,4 Animal studies have demonstrated the ability of magnetic stimulation to modify arrhythmias by targeting cardiac sympathetic innervation.5,6 In this study, the first of its type involving human participants to our knowledge, we investigated the feasibility and adverse events of TCMS for left stellate ganglion inhibition in ventricular tachycardia storm.