In municipal hospitals heavily burdened with traumatic surgery, the method employed for grouping and matching blood prior to transfusion must be chosen for speed as well as for accuracy. While meeting modern requirements for safety, the technic will of necessity be designed primarily for efficiency. At the Cincinnati General Hospital, where more than 500 transfusions are given each year in the surgical service alone, there has been a gradual evolution toward a more efficient routine for the selection of donors from groups of unknown volunteers. The procedure that we now consider ideally suited to our needs is a combination of the Vincent1 open macroscopic method for grouping and the Coca2 compatibility test for direct matching. Each method has been slightly modified, so that both determinations may be made with a single small sample of defibrinated whole blood. The Vincent and the Coca methods were reported almost simultaneously in
HOXWORTH P, AMES A. BLOOD GROUPING AND COMPATIBILITYA SIMPLE TECHNIC FOR DETERMINATION FROM SMALL AMOUNTS OF DEFIBRINATED WHOLE BLOOD. JAMA. 1937;108(15):1234–1236. doi:10.1001/jama.1937.02780150008002
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