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May 26, 2020

Deprescribing Antihypertensive Medications for Patients Aged 80 Years or Older: Is Doing Less Doing No Harm?

Author Affiliations
  • 1Duke University Medical Center, Durham, North Carolina
  • 2Washington University School of Medicine in St Louis, St Louis, Missouri
JAMA. 2020;323(20):2024-2026. doi:10.1001/jama.2020.4841

The treatment of hypertension in older adults is a major public health concern. Among the nearly 13 million persons in the United States aged 80 years or older, approximately 80% have high blood pressure (BP).1,2 Hypertension is the most potent modifiable risk factor for cardiovascular disease in older adults and has been strongly associated with stroke, myocardial infarction, heart failure, peripheral artery disease, kidney failure, and dementia. Thus, defining optimal strategies for managing elevated BP in older individuals is a high priority.