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December 1, 1945


JAMA. 1945;129(14):979-980. doi:10.1001/jama.1945.02860480059020

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[To Dr. Engelsher's communication Dr. Waldbott replies:]

To the Editor:—  The comment by Dr. Engelsher reemphasizes a number of points brought out in my paper. Concerning those on which there is some divergence of opinion, I wish to suggest the following:

  1. Glycerinated extracts, which are usually employed for intracutaneous testing, are definitely more stable than the powdered ones, which are most widely in use for scratch testing. False positive reactions occur in both methods of testing. They can easily be recognized after the extract in question has been used a few times.

  2. If intracutaneous tests are used (not scratch tests!) the injection of graduated doses of a certain antigen, either directly or by passive transfer, has been by far the most satisfactory method to me of gaging the patient's sensitivity (Waldbott, G. L.: Hay Fever Treatment During the Season, Tri-Stat'e M. J. 15:2949 [May] 1943).

  3. The intravenous

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