Despite recent advances in chemical and surgical therapy, the treatment of lung abscesses remains an important problem. The sulfonamides, pneumothorax, phrenic nerve avulsion, bronclioscopy and postural drainage have all proved to be of definite, but limited, value. The surgical treatment of lung abscesses, particularly the chronic type, still is attended by a high fatality rate. The sulfonamides have not proved to be effective except in the control of the associated pneumonitis. In the relatively short time since penicillin has been available, a few lung abscesses have been treated with this new drug. The response in some of these cases has been excellent. Recently 4 patients suffering from lung abscesses have been treated in the Wayne County General Hospital, Eloise, Mich., with penicillin. Our purpose in this communication is to review the previously reported cases of lung abscesses treated with penicillin and to present the cases which we have observed during
SMYTH CJ, BILLINGSLEA TH. THE TREATMENT OF LUNG ABSCESSES WITH PENICILLIN: REPORT OF FOUR CASES. JAMA. 1945;129(15):1005–1010. doi:10.1001/jama.1945.02860490017005
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