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Comment & Response
July 28, 2020

Pathogenic Variants in Breast Cancer Susceptibility Genes in Older Women

Author Affiliations
  • 1Molecular Diagnostics Laboratory, INRaSTES, National Centre for Scientific Research Demokritos, Athens, Greece
JAMA. 2020;324(4):397. doi:10.1001/jama.2020.7986

To the Editor The advent of sequencing technologies has brought genetic information to the forefront of clinical decision-making for cancer patients. Universal germline testing for hereditary cancer is not yet recommended; rather, there are guidelines on who to test based on certain features suggestive of hereditary predisposition, such as early age at diagnosis and family history.1,2

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