Polymyalgia rheumatica (PMR) should be included in the differential diagnosis of patients with acute onset of bilateral upper extremity pain, which is often worse with or following rest.1 Giant cell arteritis (GCA) is characterized by headache and sometimes acute vision loss. PMR and GCA almost exclusively affect persons aged at least 50 years and frequently have overlapping symptoms, such as fever, fatigue, weight loss, depression, and night sweats, and elevations of inflammatory markers, such as erythrocyte sedimentation rate and C-reactive protein. Based on data from 2015, the overall age- and sex-adjusted prevalence rate in the US of PMR was estimated at 701 per 100 000 population aged at least 50 years and of GCA was estimated at 204 per 100 000 population aged at least 50 years.2 This JAMA Insights article provides an update for a previous review and a suggested algorithm for the diagnosis and management of PMR and CGA.1
Identify all potential conflicts of interest that might be relevant to your comment.
Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.
Err on the side of full disclosure.
If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.
Not all submitted comments are published. Please see our commenting policy for details.
Buttgereit F, Matteson EL, Dejaco C. Polymyalgia Rheumatica and Giant Cell Arteritis. JAMA. 2020;324(10):993–994. doi:10.1001/jama.2020.10155
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: