[Skip to Navigation]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 34.236.187.155. Please contact the publisher to request reinstatement.
Views 12,669
Citations 0
JAMA Diagnostic Test Interpretation
October 30, 2020

Urinary Magnesium in the Evaluation of Hypomagnesemia

Author Affiliations
  • 1Section of Nephrology, Department of Medicine, Baylor College of Medicine, Houston, Texas
  • 2Section on Nephrology, Wake Forest School of Medicine, Winston-Salem, North Carolina
JAMA. 2020;324(22):2320-2321. doi:10.1001/jama.2020.18400

A 63-year-old woman with a medical history of type 2 diabetes, atrial fibrillation, hypothyroidism, and hypertension was referred for refractory hypomagnesemia. Her blood pressure was 148/68 mm Hg, heart rate 96/min, and weight 106.4 kg. Medications included liraglutide, metformin, apixaban, sotalol, metoprolol, levothyroxine, venlafaxine, lisinopril, ranitidine, and magnesium oxide (400 mg, 2 times/d). Her prior serum magnesium levels ranged from 1.4 mg/dL to 1.6 mg/dL and a recent hemoglobin A1c level was 10.8%. Following baseline blood testing (Table), the patient collected a 24-hour urine sample after discontinuing magnesium supplements for 24 hours.

Limit 200 characters
Limit 25 characters
Conflicts of Interest Disclosure

Identify all potential conflicts of interest that might be relevant to your comment.

Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.

Err on the side of full disclosure.

If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.

Not all submitted comments are published. Please see our commenting policy for details.

Limit 140 characters
Limit 3600 characters or approximately 600 words
    ×