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Clinical Trials Update
November 24, 2020

Fecal Transplant for Clostridioides difficile Effective in Practice

JAMA. 2020;324(20):2020. doi:10.1001/jama.2020.22572

A single fecal microbiota transplant (FMT) cured nearly all patients with Clostridioides difficile infection (CDI) in a study published in Gastroenterology.

The study reported outcomes from the first 259 pediatric and adult patients at 20 North American clinics enrolled in the FMT National Registry. Participants, for whom standard anti-CDI therapy had failed, mostly had moderate or mild CDI with a median duration of 20 weeks.