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To the Editor:—
In the article entitled "The Addis Count in Children Following Clinical Recovery from Postinfectious Nephritis," by H. H. Boyle, C. A. Aldrich, Albert Frank and Sydney Borowsky, Chicago (The Journal, May 1, p. 1496), the statement is made that "a difference of one cell per square in the chamber makes a difference of 10,000 in the total specimen."Feeling that this statement is somewhat misleading, I should like to clarify the method of calculation.The calculation of the total urinary sediment of the twelve-hour specimen is the object of the test. In this series (Boyle and others) from 120 to 150 cc. of urine was about the average twelve-hour output. In determining the amount of urinary sediment present in this total, a 10 cc. sample of the total is taken, centrifugated according to the accepted technic, and the supinate withdrawn by pipet, usually 1 cc. of urine
Frank A, . "THE ADDIS COUNT IN CHILDREN FOLLOWING CLINICAL RECOVERY FROM POSTINFECTIOUS NEPHRITIS". JAMA. 1937;108(22):1908. doi:10.1001/jama.1937.02780220066025
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