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The author has endeavored to find expression for the rules of biologic effects of x-rays under different conditions. Normal tissue cultures have been used as a biologic measure-factor for this purpose. He first gives a brief report of the biologic units of measure now ordinarily employed. He then discusses the adaptability of tissue culture for this purpose, giving in detail the technic employed. The histology of normal fibroblast cultures is described and reference is made to a series of examinations of the cultures. The experiments show variations in the rate of growth in different cultures in such a way that some cultures which during the experiment grow more quickly than others continue to grow more quickly during the entire experiment. The velocity of growth of the single culture from day to day shows furthermore regular oscillations, caused by different external conditions (nutrition). If a comparison of growth is made in
Röntgenbiologische Untersuchungen mit Gewebekulturen als Indikator. JAMA. 1937;108(22):1914. doi:10.1001/jama.1937.02780220072029
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