In Reply Dr Mahé and colleagues are concerned about the sensitivity and specificity of the thresholds used for diagnosing PAD in patients with normal (1.00-1.40) or borderline (0.91-0.99) resting ABI and exertional non–joint-related leg pain.1,2 The diagnostic threshold of either a postexercise ABI decrease of more than 20% or a postexercise ankle systolic pressure decrease of more than 30 mm Hg were suggested by Aboyans et al3 as a reasonable diagnostic criterion for PAD (recommendation class IIa; level of evidence A) in the 2012 American Heart Association scientific statement on measurement and interpretation of the ABI.
Mehta A, Sperling LS, Wells BJ. Postexercise Ankle-Brachial Index Testing to Diagnose Peripheral Artery Disease—Reply. JAMA. 2021;325(1):89–90. doi:10.1001/jama.2020.22490
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: