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JAMA Insights
Immune Checkpoint Inhibitor Toxicity
Douglas B. Johnson, MD; Sunandana Chandra, MD; Jeffrey A. Sosman, MD
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Original Investigation
Fatal Toxic Effects Associated With Immune Checkpoint Inhibitors
Daniel Y. Wang, MD; Joe-Elie Salem, MD; Justine V. Cohen, MD; Sunandana Chandra, MD; Christian Menzer, MD; Fei Ye, PhD; Shilin Zhao, PhD; Satya Das, MD; Kathryn E. Beckermann, MD, PhD; Lisa Ha, MSN; W. Kimryn Rathmell, MD, PhD; Kristin K. Ancell, MD; Justin M. Balko, PharmD, PhD; Caitlin Bowman, PharmD; Elizabeth J. Davis, MD; David D. Chism, MD; Leora Horn, MD; Georgina V. Long, MBBS, PhD; Matteo S. Carlino, MBBS; Benedicte Lebrun-Vignes, MD; Zeynep Eroglu, MD; Jessica C. Hassel, MD; Alexander M. Menzies, MBBS, PhD; Jeffrey A. Sosman, MD; Ryan J. Sullivan, MD; Javid J. Moslehi, MD; Douglas B. Johnson, MD
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Brief Report
Association of Resistance to Immune Checkpoint Inhibitors in Metastatic Colorectal Cancer With Misdiagnosis of Status
Romain Cohen, MD; Elisabeth Hain, MD; Olivier Buhard, MSc; Agathe Guilloux, PhD; Armelle Bardier, MD; Rachid Kaci, MD; Philippe Bertheau, MD, PhD; Florence Renaud, MD, PhD; Frédéric Bibeau, MD, PhD; Jean-François Fléjou, MD, PhD; Thierry André, MD; Magali Svrcek, MD, PhD; Alex Duval, MD, PhD
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Brief Report
Association of Toxic Effects With Shared Antigens in Non–Small Cell Lung Cancer
Fiamma Berner, MSc; David Bomze, MSc; Stefan Diem, MD; Omar Hasan Ali, MD; Mirjam Fässler, MD; Sandra Ring, MSc; Rebekka Niederer, MD; Christoph J. Ackermann, MD; Petra Baumgaertner, MSc; Natalia Pikor, PhD; Cristina Gil Cruz, PhD; Willem van de Veen, PhD; Mübeccel Akdis, MD, PhD; Sergey Nikolaev, PhD; Heinz Läubli, MD, PhD; Alfred Zippelius, MD; Fabienne Hartmann, MSc; Hung-Wei Cheng, PhD; Gideon Hönger, MSc; Mike Recher, MD; Jonathan Goldman, MD; Antonio Cozzio, MD; Martin Früh, MD; Jacques Neefjes, PhD; Christoph Driessen, MD; Burkhard Ludewig, DVM; Ahmed N. Hegazy, MD, PhD; Wolfram Jochum, MD; Daniel E. Speiser, MD; Lukas Flatz, MD
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Original Investigation
Readministration of Immune Checkpoint Inhibitors After Immune-Related Adverse Events
Audrey Simonaggio, MD; Jean Marie Michot, MD; Anne Laure Voisin, MD; Jérome Le Pavec, MD, PhD; Michael Collins, MD; Audrey Lallart, MD; Geoffray Cengizalp, MD; Aurore Vozy, MD; Ariane Laparra, MD; Andréa Varga, MD; Antoine Hollebecque, MD; Stéphane Champiat, MD, PhD; Aurélien Marabelle, MD, PhD; Christophe Massard, MD, PhD; Olivier Lambotte, MD, PhD
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Research Letter
Factors Associated With Immune Checkpoint Inhibitor–Related Myocarditis
Yoshito Zamami, PhD; Takahiro Niimura, BS; Naoto Okada, PhD; Toshihiro Koyama, PhD; Keijo Fukushima, PhD; Yuki Izawa-Ishizawa, MD, PhD; Keisuke Ishizawa, PhD
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Original Investigation
Immune Checkpoint Inhibitors and Adverse Events in Advanced Melanoma
Ching-Yuan Chang, MS; Haesuk Park, PhD; Daniel C. Malone, PhD; Ching-Yu Wang, MS; Debbie L. Wilson, PhD; Yu-Min Yeh, MD; Sascha Van Boemmel-Wegmann, PhD; Wei-Hsuan Lo-Ciganic, PhD
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Original Investigation
Immune Checkpoint Inhibitor Rechallenge After Immune-Related Adverse Events in Patients With Cancer
Charles Dolladille, MD, MSc; Stéphane Ederhy, MD; Marion Sassier, PharmD, MSc; Jennifer Cautela, MD; Franck Thuny, MD, PhD; Ariel A. Cohen, MD, PhD; Sophie Fedrizzi, PharmD, MSc; Basile Chrétien, PharmD, MSc; Angélique Da-Silva, MD; Anne-Flore Plane, MD, MSc; Damien Legallois, MD, MSc; Paul U. Milliez, MD, PhD; Véronique Lelong-Boulouard, PharmD, PhD; Joachim Alexandre, MD, PhD
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Research Letter
Association of Impaired Spermatogenesis With the Use of Immune Checkpoint Inhibitors for Metastatic Melanoma
Jason M. Scovell, MD, PhD; Karl Benz, MD; Iryna Samarska, MD, PhD; Taylor P. Kohn, MD; Jody E. Hooper, MD; Andres Matoso, MD; Amin S. Herati, MD
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Brief Report
Multisystem Immune-Related Adverse Events Associated With Immune Checkpoint Inhibitors In NSCLC
Bairavi Shankar, BA; Jiajia Zhang, MD, MPH; Abdul Rafeh Naqash, MD; Patrick M. Forde, MBBCh; Josephine L. Feliciano, MD; Kristen A. Marrone, MD; David S. Ettinger, MD; Christine L. Hann, MD, PhD; Julie R. Brahmer, MD; Biagio Ricciuti, MD; Dwight Owen, MD, MS; Yukihiro Toi, MD; Paul Walker, MD; Gregory A. Otterson, MD; Sandip H. Patel, MBBS; Shunichi Sugawara, MD; Jarushka Naidoo, MBBCH, MHS
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Comment & Response
Immune Checkpoint Inhibitor Therapy Toxicities—Reply
Adam S. Cifu, MD; Anne R. Bass, MD; Pankti D. Reid, MD, MPH
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Comment & Response
Immune Checkpoint Inhibitor Therapy Toxicities
Heather S. L. Jim, PhD; Hans Knoop, PhD; Adam P. Dicker, MD, PhD