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June 19, 1937


JAMA. 1937;108(25):2102-2109. doi:10.1001/jama.1937.02780250016005

Since the work of Buerger, who described the characteristic lesions of the vascular walls in thromboangiitis obliterans and thus distinguished it from other diseases of the blood vessels, attention has been directed, quite naturally, toward the differences between this disease and arteriosclerosis rather than to those features which they have in common.

Reports in the literature record several kinds of medical treatment of thrombo-angiitis obliterans which have resulted in arrest of the disease and a marked reduction in amputations, but we have failed to find reports of similar treatment applied in cases of arteriosclerosis. We have stressed the features common to the two diseases and, with therapy based on the likenesses of rather than on the differences between the two, we have obtained results in arteriosclerosis even more favorable than those in thrombo-angiitis obliterans.

The decreased peripheral blood supply in both diseases is due in part to functional constriction of

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