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July 3, 1937

LEUKOCYTE BEHAVIOR DURING GASTRIC ANALYSIS: A CRITICAL STUDY OF THE "LEUKOPENIC INDEX"

Author Affiliations

PHILADELPHIA

From the Gastro-Intestinal Clinic of Temple University Medical School.

JAMA. 1937;109(1):23-25. doi:10.1001/jama.1937.02780270025008
Abstract

In 1931 Kern1 suggested that there might be some relation between peptic ulcer and allergy; in 1934 Vaughan2 seemed to prove a definite relationship between leukopenia and food allergy; still later Rinkel3 and Zeller4 added their similar work, and only last year Gay5 stated that peptic ulcer may in some instances be associated with a definite food sensitivity.

It would therefore seem logical to suppose that, if such cases were to be found, they would be open to discovery in a gastro-intestinal clinic, especially such a clinic as ours, which uses the Ewald test meal of bread and water, the bread containing those most usual and powerful allergens milk and wheat.

The problem that presents itself was consequently twofold: to study, first of all, leukocyte behavior during 100 consecutive gastric analyses, with no preconceived bias, with no limitation as to type of case considered or

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