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With the introduction of a satisfactory drug for intravenous pyelography, Swick and von Lichtenberg made a valuable addition to diagnostic methods. How useful this method will become, what its disadvantages and dangers may be, and to what extent it will replace some of the older methods will be determined only by a long experience with its use.
The basis for this report is an analysis of the results obtained with iopax (introduced as "Uroselectan") in forty-five cases in which forty-seven injections were done. In all our cases a sterile, freshly prepared 40 per cent solution of iopax was injected directly and slowly into the vein. The usual dose for adults was 40 Gm., although in a few cases in which there was poor renal function or in which this amount had not given the desired results, larger doses were used. In children smaller doses were used, usually about 25 Gm.
JOELSON JJ, ZOLLINGER R. IOPAX: AN ANALYSIS OF THE RESULTS OBTAINED IN FORTY-FIVE CASES, WITH REPORT OF A CASE SHOWING A SEVERE REACTION FOLLOWING INJECTION OF IOPAX. JAMA. 1932;98(10):799–803. doi:10.1001/jama.1932.02730360021005
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