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Research Letter
April 27, 2021

HPV Vaccination Among Young Adults in the US

Author Affiliations
  • 1Department of Otolaryngology–Head and Neck Surgery, University of Michigan, Ann Arbor
  • 2University of Michigan Medical School, Ann Arbor
  • 3Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor
  • 4Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor
  • 5Department of Surgery, University of Michigan, Ann Arbor
JAMA. 2021;325(16):1673-1674. doi:10.1001/jama.2021.0725

The human papillomavirus (HPV) vaccine was approved for females in 2006 and males in 2009 for the prevention of anogenital cancer and warts. The indications were expanded in 2020 to include the prevention of oropharyngeal cancer, which is more common in males.1 The Advisory Committee on Immunization Practices recommends routine vaccination with 2 doses at age 11 to 12 years, with catch-up vaccination at age 13 to 26 years (limited to age 13-21 years from 2011 to 2019 for males).2 If the first dose occurs after age 15 years, a 3-dose series is recommended.2

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