Immune-mediated inflammatory diseases, such as rheumatoid arthritis (RA), psoriatic arthritis, axial spondyloarthritis, and inflammatory bowel disease, are complex disorders for which an increasing number of therapies are available. Targeted immunomodulatory therapies for these conditions are drugs that modify the immune system response to treat disease. The best medical strategies by which these medications might attain the most optimal outcomes remains unclear.1 In this issue of JAMA, 2 randomized clinical trials from Norway2,3 tested different approaches to prescribing immunomodulatory treatments to improve outcomes for individual patients.
Curtis JR, Ogdie A, George MD. Treatment Strategies for Patients With Immune-Mediated Inflammatory Diseases. JAMA. 2021;325(17):1726–1728. doi:10.1001/jama.2021.2740
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