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July 17, 1937

Complement or Alexin

JAMA. 1937;109(3):232. doi:10.1001/jama.1937.02780290054033

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This monograph reviews the writings about complement, the thermolabile element in the blood which in combination with specific immune bodies causes the destruction of bacteria and foreign red cells. After the introductory consideration come chapters on the constitution of complement, the scope of its activity, factors influencing its action in vitro, the nature of its action and possibly related phenomena, its presence in the blood stream, its origin in the body and its variations in vivo. In discussing the constitution of complement the author calls the midpiece and the endpiece "midstuk" and "endstuk," but there seems to be no need for any such words in English. Throughout the book Friedberger is misspelled Friedburger. The book will be helpful to students of complement. It records the slow advance in our understanding of that principle by exhaustive research, although it is forced to catalogue many discordant results. One may well agree with

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