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July 24, 1937

GAS GANGRENE TREATED WITH SULFANILAMIDE: REPORT OF THREE CASES

Author Affiliations

Instructor in Orthopedic Surgery, Johns Hopkins University School of Medicine BALTIMORE

JAMA. 1937;109(4):254-256. doi:10.1001/jama.1937.02780300010005
Abstract

Search of the literature fails to reveal the use of sulfanilamide1 heretofore in the treatment of gas gangrene. It appears to be a valuable adjunct in this respect and offers great promise with regard to saving of limb and life.

Case 1.—  W. C., a Negro youth aged 15, admitted to Franklin Square Hospital Jan. 12, 1937, after being struck by an automobile while roller skating, suffered mild shock and concussion, a transverse fracture of the right femur in the mid third, and a compound fracture of the left femur in the lower third which extended longitudinally through the metaphysis and involved the outer half of the epiphyseal cartilage plate; the proximal fragment protruded through the lateral surface of the thigh above the knee. The wound area was treated, the compound fracture was reduced, dressings of dry gauze were applied, and both fractures were splinted; 1,500 units of tetanus

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