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Clinical Trials Update
May 25, 2021

Patients Favor Surgical Repair of Ruptured ACL

JAMA. 2021;325(20):2039. doi:10.1001/jama.2021.7718

Patients with acute rupture of the anterior cruciate ligament (ACL) who had early surgical reconstruction perceived their symptoms, knee function, and ability to play sports more positively after 2 years than patients who had rehabilitation followed by surgery, if needed. But the clinical importance of the findings reported in The BMJ is unclear because 50% of the rehabilitation group recovered without surgery.

Conducted at 6 hospitals in the Netherlands, the trial randomized 167 adults to early arthroscopic ACL reconstruction or to physical therapy for at least 3 months followed by optional reconstruction.