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Comment & Response
May 25, 2021

Effect of Sodium Nitrite on Survival of Cardiac Arrest to Hospital Admission—Reply

Author Affiliations
  • 1Department of Medicine, University of Washington, Seattle
  • 2Department of Health Services, University of Washington, Seattle
JAMA. 2021;325(20):2118-2119. doi:10.1001/jama.2021.4067

In Reply Mr Sang and Dr Xu discuss potential explanations for the lack of benefit seen in our study with the use of sodium nitrite during resuscitation after out-of-hospital cardiac arrest.1 They cite 2 potential reasons for this lack of benefit: a delay in nitrite administration compared with animal studies and a potential benefit of sodium nitrite in certain subgroups of patients.

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