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July 31, 1937

THE TREATMENT OF LUNG ABSCESS BY MEANS OF GUAIACOL INTRAVENOUSLY: AN ANALYSIS OF TWENTY CASES

Author Affiliations

Director, Fourth Medical Division, Bellevue Hospital; Associate Visiting Physician, Fourth Medical Division, Bellevue Hospital; Assistant Visiting Physician, Sea View Hospital NEW YORK

JAMA. 1937;109(5):330-336. doi:10.1001/jama.1937.02780310008004
Abstract

The use of guaiacol intravenously in the treatment of lung abscess was begun in the Fourth Medical Division of Bellevue Hospital in 1922. The results obtained in the early cases were sufficiently encouraging to decide us to make a more analytic study of this method of treatment. In all about fifty cases have been so treated. This article deals with the procedure and method of carrying out the treatment and presentation of twenty cases.

It has long been noted that creosote, guaiacol and their derivatives have an almost specific action on the secondary infection occurring in open pulmonary tuberculosis but no beneficial effect on the tuberculous process per se.1 The literature on the therapeutic value of these sub stances in nontuberculous lung infections is scant and indefinite. The purpose of this study was to investigate the effects of one of these substances, guaiacol, on the course of acute and

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