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JAMA Clinical Guidelines Synopsis
June 8, 2021

Interventions for Patients With Secondary Mitral Regurgitation

Author Affiliations
  • 1Division of Cardiac Surgery, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts
  • 2Department of Medicine, University of Chicago, Chicago, Illinois
JAMA. 2021;325(22):2309-2310. doi:10.1001/jama.2021.2741

Heart failure affects more than 6 million people in the US. The prevalence is expected to increase by more than 40% by 2030.1 More than half of patients with heart failure have some degree of SMR, which can occur due to ischemic or other cardiomyopathies.1,2 The effectiveness of MV surgery in primary MR patients is well established, but its efficacy for SMR is less well known.2 Since TEER has emerged as a treatment option, guidelines for the various clinical phenotypes of SMR are important for improving outcomes.