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This is a unique volume. Dr. Frew is convinced that the most important factor in determining the characters that disease assumes in childhood is the age of the child; that although the causes of disease are constant through life, as the anatomy of the individual is constantly changing during childhood, the clinical signs manifest themselves differently at different ages. This is particularly marked during the first year, the period discussed in this volume. Some diseases are confined solely to this period, others display changes even in this short interval, while others have not yet made their appearance. He believes that this method of studying disease in childhood will produce a great advance in our knowledge of children's ailments. The author states that the facts on which the study is based are drawn with few exceptions from cases under his own care. He has analyzed 8,823 consecutive cases seen in the
Disease in Childhood: A Clinical Study. The First Year: Birth to One Month; One Month to Six Months; Six Months to One Year. JAMA. 1937;109(5):385. doi:10.1001/jama.1937.02780310063029
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