The results achieved in the first evaluation study of serodiagnostic tests for syphilis in the United States1 reflected great credit on several of the serologists who had developed original methods. In the first evaluation study a total of 14,238 comparable blood samples and 2,860 comparable spinal fluid samples were tested by thirteen American serologists. It was pointed out in the report of the committee that the actual serologic testing was done under relatively ideal conditions in the laboratories of the originators of the methods and that the results did not necessarily compare with those attained in other laboratories utilizing the same methods.
In the second evaluation study2 the committee attempted to meet more closely than was possible in the first evaluation project the conditions encountered in ordinary practice. The efficiency of thirty state, municipal or private laboratories in the performance of serodiagnostic tests for syphilis was measured. The
PARRAN T, Hazen WHH, Mahoney JF, et al. SERODIAGNOSTIC TESTS FOR SYPHILIS AS PERFORMED BY THIRTY-NINE STATE LABORATORIESA COMPARATIVE STUDY A REPORT OF THE COMMITTEE ON EVALUATION OF SERODIAGNOSTIC TESTS FOR SYPHILIS. JAMA. 1937;109(6):425–430. doi:10.1001/jama.1937.02780320027009
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