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JAMA Insights
Women's Health
July 13, 2021

Diagnosis, Evaluation, and Treatment of Adenomyosis

Author Affiliations
  • 1Division of Gynecology, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas
  • 2Gynecologic Health and Disease Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland
JAMA. 2021;326(2):177-178. doi:10.1001/jama.2020.26436

Adenomyosis, a gynecologic condition characterized by the presence of endometrial glands and stroma within the myometrium, can significantly reduce quality of life. The true prevalence of adenomyosis is unknown. Adenomyosis occurs in 8.8% to 61.5% of women undergoing hysterectomy, and rates vary widely by differences in diagnostic criteria and variations between and within pathologists.1,2 The prevalence is estimated to range from 20% to 34%, based on patients referred for pelvic imaging rather than the general population of women.2

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