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August 14, 1937


JAMA. 1937;109(7):510. doi:10.1001/jama.1937.02780330038015

The last decade has witnessed an extraordinary intensification of investigation designed to elucidate the biochemistry and physiology of the lipids. The number of publications dealing with these topics has doubled in the past ten years. The data from experimental work on lipids made it evident that this group of substances is significant in maintaining physiologic well being. The results are finding practical application, as shown by the use made of knowledge of the physiologic rôle of fat soluble vitamins, by the determination of the level of blood cholesterol as an aid in following the clinical course of diabetes mellitus, and by clinical application of experimental knowledge of factors influencing the concentration of abnormal quantities of lipid in the liver.

Certain essential fatty acids which apparently cannot be synthesized by the organism must be supplied in the diet in order to maintain the normal body processes. The Burrs1 observed that