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August 14, 1937

SENSITIVITY OF THE KOLMER COMPLEMENT FIXATION TEST

Author Affiliations

Philadelphia. Director, Research Institute of Cutaneous Medicine.

JAMA. 1937;109(7):522. doi:10.1001/jama.1937.02780330050022

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Abstract

To the Editor:—  In the editorial entitled "The Clinician and the Serologic Test for Syphilis" (The Journal, July 10, p. 134) it is stated that, in the two studies of the American Committee on Evaluation of Serodiagnostic Tests for Syphilis, this test as conducted in my laboratory gave 72.6 per cent positive reactions with specimens from syphilitic individuals.As a matter of fact, however, in the first survey (The Evaluation of Serodiagnostic Tests for Syphilis in the United States, Ven. Dis. Inform. 18, supplement 1, May 1937) it gave 75.9 per cent positive reactions in a group of 415 serums and 77.8 per cent positive reactions in a group of 110 spinal fluids from syphilitic individuals. And in the second survey, recently completed, it gave 87.2 per cent positive reactions (personal communication from Dr. W. L. Treadway, acting surgeon, U. S. Public Health Service, April 20, 1937) with the serums

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