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Editorial
August 10, 2021

Does Crystalloid Composition or Rate of Fluid Administration Make a Difference When Resuscitating Patients in the ICU?

Author Affiliations
  • 1Divisions of Pulmonary, Allergy, Critical Care and Sleep Medicine and Renal Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia
  • 2Emory Critical Care Center, Emory University School of Medicine, Atlanta, Georgia
  • 3Department of Surgery, Emory University School of Medicine, Atlanta, Georgia
JAMA. 2021;326(9):813-815. doi:10.1001/jama.2021.11119

Administration of intravenous fluids is among the most common interventions performed in intensive care units (ICUs). The first description of fluids for resuscitation of a critically ill patient occurred during the 1830s cholera outbreak in England.1 In the 200 years since, debates continue surrounding the volume, composition, and rate of fluid administration, with few definitive answers to guide clinicians.

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