There is no need to discuss here the now well known deleterious effect of a diet deficient in iodine. To Marine and his associates for their scientific discoveries, their stimulation of other workers and the dissemination of this newer knowledge is due all credit. Plummer, too, should be mentioned in any clinical talk on thyroid and iodine, as he scientifically demonstrated the early marked improvement, temporary though it may be, of patients with hyperthyroid disease from iodine administration.
Michigan lies in the center of the Great Lakes endemic goiter belt, one of the large, though not the most severe, endemic goiter areas. In these great areas both food and drinking water are known to be deficient in iodine. This deficiency in iodine is not observed uniformly throughout the so-called goiter belt. At Mount Clemens, Mich., 26 per cent of the children had enlarged thyroids, while at Romeo, Mich., 12 miles
McCLURE RD. THE INCIDENCE OF OPERATIONS FOR GOITER IN SOUTHERN MICHIGANEFFECT OF IODIZED SALT AFTER TWELVE YEARS' GENERAL USE. JAMA. 1937;109(10):782–785. doi:10.1001/jama.1937.02780360030007
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