Bicuspid aortic valve (BAV) disease is a congenital condition that affects an estimated 1% of the world’s population.1 While initial valve function is relatively normal and has little early clinical consequence, progressive valve fibrosis and calcification eventually results in severe aortic stenosis, requiring aortic valve replacement in nearly all patients with BAV in later life.
Otto CM, Newby DE. Transcatheter Valve Replacement for Bicuspid Aortic Stenosis. JAMA. 2021;326(11):1009–1010. doi:10.1001/jama.2021.13229
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