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Featured Clinical Reviews

September 21, 2021

Transcatheter Valve Replacement for Bicuspid Aortic Stenosis

Author Affiliations
  • 1Division of Cardiology, Department of Medicine, University of Washington School of Medicine, Seattle
  • 2British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom
JAMA. 2021;326(11):1009-1010. doi:10.1001/jama.2021.13229

Bicuspid aortic valve (BAV) disease is a congenital condition that affects an estimated 1% of the world’s population.1 While initial valve function is relatively normal and has little early clinical consequence, progressive valve fibrosis and calcification eventually results in severe aortic stenosis, requiring aortic valve replacement in nearly all patients with BAV in later life.

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