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JAMA Diagnostic Test Interpretation
November 16, 2021

Electrodiagnostic Testing for Diagnosing Polyneuropathy

Author Affiliations
  • 1Department of Neurological Sciences, Rush University, Chicago, Illinois
JAMA. 2021;326(19):1966-1967. doi:10.1001/jama.2021.19286

A 50-year-old woman with a history of seizures presented to the electromyography laboratory with progressive lower extremity pain and gait imbalance for approximately 5 years. A neurological examination demonstrated reduced pinprick sensation in both feet and absent vibratory sensation at the first toes. Mild weakness of ankle dorsiflexion and absent ankle jerk reflexes were noted bilaterally. She had a slightly wide-based gait, high-arched feet, and hammer toes. She had no known family history of polyneuropathy and no history of diabetes, alcohol misuse, known vitamin deficiency, hypothyroidism, or HIV. Nerve conduction studies (NCS) and needle electromyography (EMG) were performed. The results are shown in Table 1 and Table 2.

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