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October 9, 1937

UNUSUAL ASPECTS OF HYPERTHYROIDISM: CLINICAL LECTURE AT ATLANTIC CITY SESSION

Author Affiliations

LOUISVILLE, KY.

JAMA. 1937;109(15):1197-1201. doi:10.1001/jama.1937.92780410006009
Abstract

The symptoms and signs which characterize the onset and course of typical hyperthyroidism are too well known to be repeated. For the purpose of this discussion, I shall consider the effect of an increased amount of thyroxine in the circulating blood and shall not attempt to differentiate between exophthalmic goiter and the toxic adenoma of Plummer. Although there is some difference in the onset and severity of symptoms of these two types, the effect in general on the nutritional state, the nervous and circulatory systems and the reaction of the body are the same. Unquestionably, there has been and still is a tendency to depend largely on the basal metabolic rate for diagnosis. In my section of the country, at least according to my experience, in a large number of determinations an overwhelming majority are on the minus side and rates of from minus 10 to minus 15 per cent

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