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October 23, 1937

Autonomic Neuro-Effector Systems

JAMA. 1937;109(17):1392. doi:10.1001/jama.1937.02780430070047

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This monograph is timely in that it expounds in a lucid and interesting style the physiologic evidence and theory bearing on a new field of physiology which has been intensively cultivated during the last decade. This new field pertains to the concept that chemical mediators are concerned in the transmission of impulses from nerves to the muscular and glandular cells they innervate. The organization of functional activity of the autonomic system, as far as the evidence for the chemical mediation of autonomic impulses is concerned, is presented in a simple, concise and well organized manner. The essence of a large mass of literature, difficult for many to read intelligently, has been extracted and is presented so that the busy physician or student may in a few hours become familiar with this new and important subject. This field of physiology is too young to have produced numerous practical applications; yet acetylcholine,

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