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October 30, 1937

GONOCOCCIC ARTHRITIS: PATHOGENESIS, MECHANISM OF RECOVERY AND TREATMENT: CLINICAL LECTURE AT ATLANTIC CITY SESSION

Author Affiliations

BOSTON

From the Thorndike Memorial Laboratory, Second and Fourth Medical Services (Harvard), Boston City Hospital, and the Department of Medicine, Harvard University Medical School.

JAMA. 1937;109(18):1448-1453. doi:10.1001/jama.1937.92780440002012
Abstract

In an investigation of various types of arthritis, we have made detailed studies and observations on patients with gonococcic infections involving the joints. Particular interest has been taken in the pathogenesis of this disease, together with the mechanism of recovery. At this time we present a summary of the results of this study.

DIAGNOSTIC CRITERIA  The diagnosis of gonococcic arthritis was made on the following grounds: (1) a history of a recent attack of gonorrhea; (2) evidence of a localized gonococcic infection of the genital tract; (3) a positive reaction to the gonococcus complement fixation test on the blood and/or synovial fluid, and (4) the demonstration of gonococci in the synovial fluid.

CLINICAL FEATURES OF GONOCOCCIC ARTHRITIS  During the past five years, 140 cases of gonococcic arthritis have been observed and studied. Sixty-nine cases were summarized previously,1 and we not add seventy-one more cases to this first

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