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November 13, 1937


JAMA. 1937;109(20):1618-1620. doi:10.1001/jama.1937.02780460028007

Favism is a disease characterized by a rapidly developing anemia accompanied by jaundice, hematuria and hemoglobinuria, and owes its onset to the ingestion of the bean Vicia fava or to the inhalation of pollen from the blossoming plant. This bean seems to be a common article of food in the southern part of Italy, Sicily and Sardinia. Reports of the disease are not uncommon in the Italian literature and there are a few references to it, as fabismus, in the German. Although the beans are eaten by Italians resident in this country there seems to be little or no reference to it in English or American literature. A single case report of McCrae and Ullery1 in 1933 and the following personally observed instance seem the only ones described in this country:

B. B., a man, aged 21, was admitted to the hospital complaining of weakness, a yellowish tinge of

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