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A strong, heavily built man, aged about 40, suffering with a lobar pneumonia, was seen the morning of Dec. 1, 1931, at which time he had a temperature of 102 F. He had been given the recommended dosage of optochin base for three days. The afternoon of November 30, he complained of a violent headache and later in the evening stated that he was unable to distinguish light. The pupils were moderately dilated and gave a faint reaction to light. The fundus in both eyes was entirely normal. As the patient was very nervous, it was hoped that he had an hysterical amblyopia.
I next saw the patient, December 4, at which time the right fundus was normal but in the left eye, about midway between and slightly below the disk and the macula, there was a rectangular retinal hemorrhage about 2 by 3 mm. in size.
I next saw
Scales HL. AMBLYOPIA IN PNEUMONIA AFTER ETHYLHYDROCUPREINE (OPTOCHIN BASE). JAMA. 1932;98(16):1373. doi:10.1001/jama.1932.27320420002010a
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