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November 20, 1937

STUDIES ON THE PATHOLOGY OF THE RENAL PAPILLA: RELATIONSHIP TO RENAL CALCULUS

Author Affiliations

PHILADELPHIA

JAMA. 1937;109(21):1698-1702. doi:10.1001/jama.1937.02780470020006
Abstract

In three previous publications1 certain deductions were drawn relative to the origin of primary renal calculi. These deductions seem to have been thoroughly supported and proved by the research work performed and therein reported. As subsequent studies have further substantiated these facts, it is pertinent to restate them at this time:

  1. It was shown that all clinical data and all reasoning from the point of view of pathology require that a primary renal calculus must be stationary and attached while beginning and acquiring growth.

  2. Small renal calculi, when examined under a magnifying lens, almost always show such a stoma, or facet, of mural attachment.

  3. X-ray studies in proper cases repeatedly show that such primary renal calculi have their origin in the minor calices.

  4. It was postulated and subsequently proved that an initiating lesion would be found.

  5. It was postulated and subsequently proved that the

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